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Errors in protein synthesis increase the level of saturated fatty acids and affect the overall lipid profiles of yeast

The occurrence of protein synthesis errors (mistranslation) above the typical mean mistranslation level of 10(−4) is mostly deleterious to yeast, zebrafish and mammal cells. Previous yeast studies have shown that mistranslation affects fitness and deregulates genes related to lipid metabolism, but t...

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Detalles Bibliográficos
Autores principales: Araújo, Ana Rita D., Melo, Tânia, Maciel, Elisabete A., Pereira, Clara, Morais, Catarina M., Santinha, Deolinda R., Tavares, Joana F., Oliveira, Helena, Jurado, Amália S., Costa, Vítor, Domingues, Pedro, Domingues, Maria Rosário M., Santos, Manuel A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110467/
https://www.ncbi.nlm.nih.gov/pubmed/30148852
http://dx.doi.org/10.1371/journal.pone.0202402