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Optimizing treatment of tauroursodeoxycholic acid to improve embryonic development after in vitro maturation of cumulus-free oocytes in mice

Cumulus-free in vitro maturation (IVM) provides a powerful tool to manipulate immature oocytes, but IVM oocytes lead to poor development after fertilization. Supplementation of the culture medium with tauroursodeoxycholic acid (TUDCA), a bile acid, has been reported to improve the development of emb...

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Detalles Bibliográficos
Autores principales: Mochizuki, Masato, Miyagi, Kodai, Kishigami, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110502/
https://www.ncbi.nlm.nih.gov/pubmed/30148855
http://dx.doi.org/10.1371/journal.pone.0202962