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Analysis of the clinical significance of DCLK1(+) colorectal cancer using novel monoclonal antibodies against DCLK1

INTRODUCTION: Doublecortin-like kinase 1 (DCLK1) is considered a putative tumor stem cell (TSC) marker and a promising therapeutic target, as DCLK1(+) progeny cells exhibit high expression in tumors. However, the biological function of DCLK1(+) cells in tumorigenesis and tumor progression remains un...

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Detalles Bibliográficos
Autores principales: Dai, Tianqi, Hu, Yunlong, Lv, Fulian, Ozawa, Tatsuhiko, Sun, Xin, Huang, Jingjing, Han, Xiaojian, Kishi, Hiroyuki, Muraguchi, Atsushi, Jin, Aishun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110630/
https://www.ncbi.nlm.nih.gov/pubmed/30174443
http://dx.doi.org/10.2147/OTT.S169928