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Analysis of the clinical significance of DCLK1(+) colorectal cancer using novel monoclonal antibodies against DCLK1
INTRODUCTION: Doublecortin-like kinase 1 (DCLK1) is considered a putative tumor stem cell (TSC) marker and a promising therapeutic target, as DCLK1(+) progeny cells exhibit high expression in tumors. However, the biological function of DCLK1(+) cells in tumorigenesis and tumor progression remains un...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110630/ https://www.ncbi.nlm.nih.gov/pubmed/30174443 http://dx.doi.org/10.2147/OTT.S169928 |