Roles of aberrant hemichannel activities due to mutant connexin26 in the pathogenesis of KID syndrome

Germline missense mutations in GJB2 encoding connexin (Cx) 26 have been found in keratitis, ichthyosis and deafness (KID) syndrome. We explored the effects of three mouse Cx26 mutants (Cx26-G12R, -G45E and -D50N) corresponding to KID syndrome-causative human mutants on hemichannel activities leading...

Descripción completa

Detalles Bibliográficos
Autores principales: Taki, T., Takeichi, T., Sugiura, K., Akiyama, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110719/
https://www.ncbi.nlm.nih.gov/pubmed/30150638
http://dx.doi.org/10.1038/s41598-018-30757-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110719/
https://www.ncbi.nlm.nih.gov/pubmed/30150638
http://dx.doi.org/10.1038/s41598-018-30757-3

Ejemplares similares