A screening assay for Selective Dimerizing Glucocorticoid Receptor Agonists and Modulators (SEDIGRAM) that are effective against acute inflammation

It has been suggested that glucocorticoid receptor (GR) agonists that promote GR homodimerization more than standard glucocorticoids such as Dexamethasone could be more effective anti-inflammatory molecules against acute and life-threatening inflammatory conditions. To test this hypothesis, we set u...

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Detalles Bibliográficos
Autores principales: Souffriau, Jolien, Eggermont, Melanie, Van Ryckeghem, Sara, Van Looveren, Kelly, Van Wyngene, Lise, Van Hamme, Evelien, Vuylsteke, Marnik, Beyaert, Rudi, De Bosscher, Karolien, Libert, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110732/
https://www.ncbi.nlm.nih.gov/pubmed/30150712
http://dx.doi.org/10.1038/s41598-018-31150-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110732/
https://www.ncbi.nlm.nih.gov/pubmed/30150712
http://dx.doi.org/10.1038/s41598-018-31150-w

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