Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer

p21-activated kinases (Paks) play an important role in oncogenic signaling pathways and have been considered as potential therapeutic targets in various cancers. Most studies of Pak function employ gene knock-out or knock-down methods, but these approaches result in loss of both enzymatic and scaffo...

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Detalles Bibliográficos
Autores principales: Chow, H. Y., Dong, B., Valencia, C. A., Zeng, C. T., Koch, J. N., Prudnikova, T. Y., Chernoff, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110733/
https://www.ncbi.nlm.nih.gov/pubmed/30150766
http://dx.doi.org/10.1038/s41467-018-05935-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110733/
https://www.ncbi.nlm.nih.gov/pubmed/30150766
http://dx.doi.org/10.1038/s41467-018-05935-6

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