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Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer
p21-activated kinases (Paks) play an important role in oncogenic signaling pathways and have been considered as potential therapeutic targets in various cancers. Most studies of Pak function employ gene knock-out or knock-down methods, but these approaches result in loss of both enzymatic and scaffo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110733/ https://www.ncbi.nlm.nih.gov/pubmed/30150766 http://dx.doi.org/10.1038/s41467-018-05935-6 |