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Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts

Galectin-9 (Gal9) has been postulated to have anti-inflammatory properties based on the ability of exogenous Gal9 to induce apoptosis in synovial fibroblasts in animal models of rheumatoid arthritis (RA). Here we aimed to assess the potential role of endogenous Galectins, including Gal9, in the infl...

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Detalles Bibliográficos
Autores principales: Pearson, Mark J., Bik, Magdalena A., Ospelt, Caroline, Naylor, Amy J., Wehmeyer, Corinna, Jones, Simon W., Buckley, Christopher D., Gay, Steffen, Filer, Andrew, Lord, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110759/
https://www.ncbi.nlm.nih.gov/pubmed/30150656
http://dx.doi.org/10.1038/s41598-018-31173-3