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Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral disc
The adult nucleus pulposus originates from the embryonic notochord, but loss of notochordal cells with skeletal maturity in humans is thought to contribute to the onset of intervertebral disc degeneration. Thus, defining the phenotype of human embryonic/fetal notochordal cells is essential for under...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110784/ https://www.ncbi.nlm.nih.gov/pubmed/30150762 http://dx.doi.org/10.1038/s41598-018-31172-4 |