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Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral disc

The adult nucleus pulposus originates from the embryonic notochord, but loss of notochordal cells with skeletal maturity in humans is thought to contribute to the onset of intervertebral disc degeneration. Thus, defining the phenotype of human embryonic/fetal notochordal cells is essential for under...

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Detalles Bibliográficos
Autores principales:	Rodrigues-Pinto, Ricardo, Ward, Lizzy, Humphreys, Matthew, Zeef, Leo A. H., Berry, Andrew, Hanley, Karen Piper, Hanley, Neil, Richardson, Stephen M., Hoyland, Judith A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110784/ https://www.ncbi.nlm.nih.gov/pubmed/30150762 http://dx.doi.org/10.1038/s41598-018-31172-4

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