Focused Ultrasound-Induced Blood-Brain Barrier Opening Enhances GSK-3 Inhibitor Delivery for Amyloid-Beta Plaque Reduction

Alzheimer’s disease (AD) is a neurodegenerative disease that is the leading cause of age-related dementia. Currently, therapeutic agent delivery to the CNS is a valued approach for AD therapy. Unfortunately, the CNS penetration is greatly hampered by the blood-brain barrier (BBB). Focused-ultrasound...

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Detalles Bibliográficos
Autores principales: Hsu, Po-Hung, Lin, Ya-Tin, Chung, Yi-Hsiu, Lin, Kun-Ju, Yang, Liang-Yo, Yen, Tzu-Chen, Liu, Hao-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110796/
https://www.ncbi.nlm.nih.gov/pubmed/30150769
http://dx.doi.org/10.1038/s41598-018-31071-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110796/
https://www.ncbi.nlm.nih.gov/pubmed/30150769
http://dx.doi.org/10.1038/s41598-018-31071-8

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