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Beneficial Role of Rosuvastatin in Blood–Brain Barrier Damage Following Experimental Ischemic Stroke

Hemorrhage transformation is the most challenging preventable complication in thrombolytic therapy and is related to recombinant tissue plasminogen activator (rt-PA)-induced blood–brain barrier (BBB) damage. Intraperitoneal injections of normal or high doses of rosuvastatin were administered to Balb...

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Detalles Bibliográficos
Autores principales: Lu, Dan, Mai, Hong-Cheng, Liang, Yu-Bin, Xu, Bing-Dong, Xu, An-Ding, Zhang, Yu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110873/
https://www.ncbi.nlm.nih.gov/pubmed/30186167
http://dx.doi.org/10.3389/fphar.2018.00926