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SLC6A3 Polymorphism Predisposes to Dopamine Overdose in Parkinson's Disease

In Parkinson's disease (PD), cognitive functions mediated by brain regions innervated by ventral tegmental area (VTA) worsen with dopamine replacement therapy, whereas processes relying on regions innervated by the substantia nigra pars compacta (SNc) improve. The SLC6A3 gene encodes the dopami...

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Detalles Bibliográficos
Autores principales: Robertson, Brian D., Al Jaja, Abdullah S., MacDonald, Alex A., Hiebert, Nole M., Tamjeedi, Ruzbeh, Seergobin, Ken N., Schwarz, Ute I., Kim, Richard B., MacDonald, Penny A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110885/
https://www.ncbi.nlm.nih.gov/pubmed/30186226
http://dx.doi.org/10.3389/fneur.2018.00693