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The Key Role of c-Fos for Immune Regulation and Bacterial Dissemination in Brucella Infected Macrophage
The cellular oncogene c-Fos (c-Fos) is a component of activator protein 1 (AP1), a master transcriptional regulator of cells. The suppression of c-Fos signaling by siRNA treatment resulted in significant induction of TLR4, which subsequently activates p38 and ERK1/2 mitogen-activated protein kinases...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110913/ https://www.ncbi.nlm.nih.gov/pubmed/30186773 http://dx.doi.org/10.3389/fcimb.2018.00287 |