In vitro genotoxicity studies: n-Butyl acrylate L5178Y mouse lymphoma (TK+/− locus assay), 2-Ethylhexyl acrylate gene mutation assay in Chinese hamster V79 cells, and 2-Ethylhexyl acrylate micronucleus test in human lymphocytes

Available point mutation tests have shown inconsistent results with various acrylates. Most of those tests were performed prior to OECD guidelines and appropriate data regarding cytotoxicity are not given. Data from three current OECD guideline compliant experiments conducted under GLP are provided....

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Detalles Bibliográficos
Autores principales: Murphy, Sandra, Ellis-Hutchings, Robert, Finch, Lavorgie, Welz, Stefanie, Wiench, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Pharmacology, Toxicology and Pharmaceutical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111055/
https://www.ncbi.nlm.nih.gov/pubmed/30167439
http://dx.doi.org/10.1016/j.dib.2018.06.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111055/
https://www.ncbi.nlm.nih.gov/pubmed/30167439
http://dx.doi.org/10.1016/j.dib.2018.06.008

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