Ibuprofen nanocrystals developed by 2(2) factorial design experiment: A new approach for poorly water-soluble drugs

The reduction of the particle size of drugs of pharmaceutical interest down to the nano-sized range has dramatically changed their physicochemical properties. The greatest disadvantage of nanocrystals is their inherent instability, due to the risk of crystal growth. Thus, the selection of an appropr...

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Detalles Bibliográficos
Autores principales: Fernandes, A.R., Ferreira, N.R., Fangueiro, J.F., Santos, A.C., Veiga, F.J., Cabral, C., Silva, A.M., Souto, E.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111112/
https://www.ncbi.nlm.nih.gov/pubmed/30166898
http://dx.doi.org/10.1016/j.jsps.2017.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111112/
https://www.ncbi.nlm.nih.gov/pubmed/30166898
http://dx.doi.org/10.1016/j.jsps.2017.07.004

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