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Development, stability and in vitro delivery profile of new loratadine-loaded nanoparticles

Purpose: Loratadine is used as antihistaminic without side effects in nervous systems. This drug is a weak base and it is absorbed from the intestine. The nitrogen of the pyridine ring is protonated in the stomach affecting the oral bioavailability. The aim of this paper was obtaining, characterize...

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Detalles Bibliográficos
Autores principales: Rodriguez Amado, Jesus Rafael, Prada, Ariadna Lafourcade, Duarte, Jonatas Lobato, Keita, Hady, da Silva, Heitor Rivero, Ferreira, Adriana Maciel, Sosa, Edgar Hernandez, Carvalho, Jose Carlos Tavares
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111125/
https://www.ncbi.nlm.nih.gov/pubmed/30166904
http://dx.doi.org/10.1016/j.jsps.2017.07.008