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Development, stability and in vitro delivery profile of new loratadine-loaded nanoparticles
Purpose: Loratadine is used as antihistaminic without side effects in nervous systems. This drug is a weak base and it is absorbed from the intestine. The nitrogen of the pyridine ring is protonated in the stomach affecting the oral bioavailability. The aim of this paper was obtaining, characterize...
Autores principales: | Rodriguez Amado, Jesus Rafael, Prada, Ariadna Lafourcade, Duarte, Jonatas Lobato, Keita, Hady, da Silva, Heitor Rivero, Ferreira, Adriana Maciel, Sosa, Edgar Hernandez, Carvalho, Jose Carlos Tavares |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111125/ https://www.ncbi.nlm.nih.gov/pubmed/30166904 http://dx.doi.org/10.1016/j.jsps.2017.07.008 |
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