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P-glycoprotein polymorphism and levothyroxine bioavailability in hypothyroid patients
OBJECTIVES: P-glycoprotein (P-gp) contributes to the disposition of a wide variety of drugs; therefore, single nucleotide polymorphisms (SNPs) in the P-gp coding gene might affect its activity. It is well known that personalized medicine, instead of empirical treatment, is a clinically important app...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111188/ https://www.ncbi.nlm.nih.gov/pubmed/30166928 http://dx.doi.org/10.1016/j.jsps.2017.11.012 |