Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration

Thousands of genes have been implicated in retinal regeneration, but only a few have been shown to impact the regenerative capacity of Müller glia—an adult retinal stem cell with untapped therapeutic potential. Similarly, among nearly 300 genetic loci associated with human retinal disease, the major...

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Detalles Bibliográficos
Autores principales: Unal Eroglu, Arife, Mulligan, Timothy S., Zhang, Liyun, White, David T., Sengupta, Sumitra, Nie, Cathy, Lu, Noela Y., Qian, Jiang, Xu, Lisha, Pei, Wuhong, Burgess, Shawn M., Saxena, Meera T., Mumm, Jeff S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111214/
https://www.ncbi.nlm.nih.gov/pubmed/30186835
http://dx.doi.org/10.3389/fcell.2018.00088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111214/
https://www.ncbi.nlm.nih.gov/pubmed/30186835
http://dx.doi.org/10.3389/fcell.2018.00088

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