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Structure-Function Relationships of the Neisserial EptA Enzyme Responsible for Phosphoethanolamine Decoration of Lipid A: Rationale for Drug Targeting
Bacteria cause disease by two general mechanisms: the action of their toxins on host cells and induction of a pro-inflammatory response that can lead to a deleterious cytokine/chemokine response (e.g., the so-called cytokine storm) often seen in bacteremia/septicemia. These major mechanisms may over...
Autores principales: | Kahler, Charlene M., Nawrocki, K. L., Anandan, A., Vrielink, Alice, Shafer, William M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111236/ https://www.ncbi.nlm.nih.gov/pubmed/30186254 http://dx.doi.org/10.3389/fmicb.2018.01922 |
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