Distinct Occurrence of Proarrhythmic Afterdepolarizations in Atrial Versus Ventricular Cardiomyocytes: Implications for Translational Research on Atrial Arrhythmia

Background: Principal mechanisms of arrhythmia have been derived from ventricular but not atrial cardiomyocytes of animal models despite higher prevalence of atrial arrhythmia (e.g., atrial fibrillation). Due to significant ultrastructural and functional differences, a simple transfer of ventricular...

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Detalles Bibliográficos
Autores principales: Bögeholz, Nils, Pauls, Paul, Dechering, Dirk G., Frommeyer, Gerrit, Goldhaber, Joshua I., Pott, Christian, Eckardt, Lars, Müller, Frank U., Schulte, Jan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111493/
https://www.ncbi.nlm.nih.gov/pubmed/30186171
http://dx.doi.org/10.3389/fphar.2018.00933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111493/
https://www.ncbi.nlm.nih.gov/pubmed/30186171
http://dx.doi.org/10.3389/fphar.2018.00933

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