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Inhibition of GSK3 and MEK induced cancer stem cell generation via the Wnt and MEK signaling pathways

Cancer stem cells (CSCs) are considered to be tumor-initiating cells, responsible for tumor invasive growth and dissemination to distant organ sites. Typically, radiation treatment and chemotherapy should target CSCs. However, current research investigating CSCs is impeded by the difficulty of isola...

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Detalles Bibliográficos
Autores principales: Liao, Shengtao, Gan, Li, Qin, Wanxiang, Liu, Chang, Mei, Zhechuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111576/
https://www.ncbi.nlm.nih.gov/pubmed/30066938
http://dx.doi.org/10.3892/or.2018.6600