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Inhibition of GSK3 and MEK induced cancer stem cell generation via the Wnt and MEK signaling pathways
Cancer stem cells (CSCs) are considered to be tumor-initiating cells, responsible for tumor invasive growth and dissemination to distant organ sites. Typically, radiation treatment and chemotherapy should target CSCs. However, current research investigating CSCs is impeded by the difficulty of isola...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111576/ https://www.ncbi.nlm.nih.gov/pubmed/30066938 http://dx.doi.org/10.3892/or.2018.6600 |