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Emodin induces apoptosis in human hepatocellular carcinoma HepaRG cells via the mitochondrial caspase-dependent pathway

Emodin-induced hepatotoxicity in vivo and in vitro has been gaining increasing attention. However, the exact molecular pathways underlying these effects remain poorly clarified. The aim of the present study was to evaluate the cytotoxic effect of emodin on HepaRG cells and to define the underlying m...

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Detalles Bibliográficos
Autores principales: Dong, Xiaoxv, Ni, Boran, Fu, Jing, Yin, Xingbin, You, Longtai, Leng, Xin, Liang, Xiao, Ni, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111625/
https://www.ncbi.nlm.nih.gov/pubmed/30106438
http://dx.doi.org/10.3892/or.2018.6620