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Mechanisms of enhanced antiglioma efficacy of polysorbate 80‐modified paclitaxel‐loaded PLGA nanoparticles by focused ultrasound

The presence of blood‐brain barrier (BBB) greatly limits the availability of drugs and their efficacy against glioma. Focused ultrasound (FUS) can induce transient and local BBB opening for enhanced drug delivery. Here, we developed polysorbate 80‐modified paclitaxel‐loaded PLGA nanoparticles (PS‐80...

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Detalles Bibliográficos
Autores principales: Li, Yingjia, Wu, Manxiang, Zhang, Nisi, Tang, Caiyun, Jiang, Peng, Liu, Xin, Yan, Fei, Zheng, Hairong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111803/
https://www.ncbi.nlm.nih.gov/pubmed/29956460
http://dx.doi.org/10.1111/jcmm.13695