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NEDD4‐induced degradative ubiquitination of phosphatidylinositol 4‐phosphate 5‐kinase α and its implication in breast cancer cell proliferation

Phosphatidylinositol 4‐phosphate 5‐kinase (PIP5K) family members generate phosphatidylinositol 4,5‐bisphosphate (PIP2), a critical lipid regulator of diverse physiological processes. The PIP5K‐dependent PIP2 generation can also act upstream of the oncogenic phosphatidylinositol 3‐kinase (PI3K)/Akt p...

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Detalles Bibliográficos
Autores principales: Tran, Mai Hoang, Seo, Eunjeong, Min, Soohong, Nguyen, Quynh‐Anh T., Choi, Juyong, Lee, Uk‐Jin, Hong, Soon‐Sun, Kang, Hyuk, Mansukhani, Alka, Jou, Ilo, Lee, Sang Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111810/
https://www.ncbi.nlm.nih.gov/pubmed/29851245
http://dx.doi.org/10.1111/jcmm.13689