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In vitro and clinical data analysis of Osteopontin as a prognostic indicator in colorectal cancer

Osteopontin (OPN) has been shown to promote colorectal cancer (CRC) progression; however, the mechanism of OPN‐induced CRC progression is largely unknown. In this study, we found that OPN overexpression led to enhanced anchorage‐independent growth, cell migration and invasion in KRAS gene mutant cel...

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Detalles Bibliográficos
Autores principales: Wei, Ran, Wong, Janet Pik Ching, Lyu, Peng, Xi, Xinping, Tong, Olivia, Zhang, Shu‐Dong, Yuen, Hiu Fung, Shirasawa, Senji, Kwok, Hang Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111822/
https://www.ncbi.nlm.nih.gov/pubmed/29851214
http://dx.doi.org/10.1111/jcmm.13686