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Prospective Use of High-Refractive Index Materials for Single Molecule Detection in Flow Cytometry

Phenotyping extracellular vesicles (EVs), where surface receptor expression is often as low as one molecule per EV, remains problematic due to the inability of commercial flow cytometers to provide single-fluorescent molecule sensitivity. While EVs are widely considered to be of great potential as d...

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Detalles Bibliográficos
Autores principales: Welsh, Joshua A., Kepley, Julia, Rosner, Ariel, Horak, Peter, Berzofsky, Jay A., Jones, Jennifer C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111846/
https://www.ncbi.nlm.nih.gov/pubmed/30071576
http://dx.doi.org/10.3390/s18082461