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Cardioprotection of ischaemic preconditioning is associated with inhibition of translocation of MLKL within the plasma membrane

Necroptosis, a form of cell loss involving the RIP1‐RIP3‐MLKL axis, has been identified in cardiac pathologies while its inhibition is cardioprotective. We investigated whether the improvement of heart function because of ischaemic preconditioning is associated with mitigation of necroptotic signali...

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Detalles Bibliográficos
Autores principales: Szobi, Adrián, Farkašová‐Ledvényiová, Veronika, Lichý, Martin, Muráriková, Martina, Čarnická, Slávka, Ravingerová, Tatiana, Adameová, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111849/
https://www.ncbi.nlm.nih.gov/pubmed/29921042
http://dx.doi.org/10.1111/jcmm.13697