Deoxycholic acid activates epidermal growth factor receptor and promotes intestinal carcinogenesis by ADAM17‐dependent ligand release

High fat diet is implicated in the elevated deoxycholic acid (DCA) in the intestine and correlated with increased colon cancer risk. However, the potential mechanisms of intestinal carcinogenesis by DCA remain unclarified. Here, we investigated the carcinogenic effects and mechanisms of DCA using th...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Wenxiao, Liu, Li, Dou, Yan, Xu, Mengque, Liu, Tianyu, Wang, Sinan, Zhang, Yujie, Deng, Baoru, Wang, Bangmao, Cao, Hailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111862/
https://www.ncbi.nlm.nih.gov/pubmed/29956475
http://dx.doi.org/10.1111/jcmm.13709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111862/
https://www.ncbi.nlm.nih.gov/pubmed/29956475
http://dx.doi.org/10.1111/jcmm.13709

Ejemplares similares