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CIP2A facilitates the G1/S cell cycle transition via B‐Myb in human papillomavirus 16 oncoprotein E6‐expressing cells

Infection with high‐risk human papillomaviruses (HR‐HPVs, including HPV‐16, HPV‐18, HPV‐31) plays a central aetiologic role in the development of cervical carcinoma. The transforming properties of HR‐HPVs mainly reside in viral oncoproteins E6 and E7. E6 protein degrades the tumour suppressor p53 an...

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Detalles Bibliográficos
Autores principales: Tian, Yonghao, Chen, Hanxiang, Qiao, Lijun, Zhang, Wenhao, Zheng, Jingyi, Zhao, Weiming, Chen, Jason. J., Zhang, Weifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111863/
https://www.ncbi.nlm.nih.gov/pubmed/29893470
http://dx.doi.org/10.1111/jcmm.13693