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Astragaloside IV modulates TGF‐β1‐dependent epithelial‐mesenchymal transition in bleomycin‐induced pulmonary fibrosis

Epithelial‐mesenchymal transition (EMT) plays an important role in idiopathic pulmonary fibrosis (IPF). Astragaloside IV (ASV), a natural saponin from astragalus membranaceus, has shown anti‐fibrotic property in bleomycin (BLM)‐induced pulmonary fibrosis. The current study was undertaken to determin...

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Detalles Bibliográficos
Autores principales: Qian, Weibin, Cai, Xinrui, Qian, Qiuhai, Zhang, Wei, Wang, Dongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111865/
https://www.ncbi.nlm.nih.gov/pubmed/29971947
http://dx.doi.org/10.1111/jcmm.13725