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Signalling through Src family kinase isoforms is not redundant in models of thrombo‐inflammatory vascular disease

The Src family kinases (SFK) are a group of signalling molecules with important regulatory functions in inflammation and haemostasis. Leucocytes and platelets express multiple isoforms of the SFKs. Previous studies used broad‐spectrum pharmacological inhibitors, or murine models deficient in multipl...

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Detalles Bibliográficos
Autores principales: Harrison, Matthew J., Chimen, Myriam, Hussain, Mohammed, Iqbal, Asif J., Senis, Yotis A., Nash, Gerard B., Watson, Steve P., Rainger, G. Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111872/
https://www.ncbi.nlm.nih.gov/pubmed/29974666
http://dx.doi.org/10.1111/jcmm.13721