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Effect of phospholipase A(2) inhibitors during infection caused by Leishmania (Leishmania) amazonensis

BACKGROUND: Lipid metabolites play an important role in parasite differentiation and virulence. Studies have revealed that Leishmania sp. uses prostaglandins to evade innate barriers, thus enabling the parasites to survive inside immune cells. Despite the role of the enzyme Phospholipase A(2) (PLA(2...

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Detalles Bibliográficos
Autores principales: Bordon, Maria L. A. C., Laurenti, Márcia D., Ribeiro, Susan Pereira, Toyama, Marcos H., Toyama, Daniela de O., Passero, Luiz Felipe D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112134/
https://www.ncbi.nlm.nih.gov/pubmed/30181736
http://dx.doi.org/10.1186/s40409-018-0156-9