TERT and Akt Are Involved in the Par-4-Dependent Apoptosis of Islet β Cells in Type 2 Diabetes

Islet β cell apoptosis plays an important role in type 2 diabetes. We previously reported that Par-4-mediated islet β cell apoptosis is induced by high-glucose/fatty acid levels. In the present study, we show that Par-4, which is induced by high-glucose/fatty acid levels, interacts with and inhibits...

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Detalles Bibliográficos
Autores principales: Liu, Chen, QiNan, Wu, XiaoTian, Lei, MengLiu, Yang, XiaGuang, Gan, WeiLing, Leng, ZiWen, Liang, Ling, Zhang, GangYi, Yang, Bing, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112224/
https://www.ncbi.nlm.nih.gov/pubmed/30186877
http://dx.doi.org/10.1155/2018/7653904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112224/
https://www.ncbi.nlm.nih.gov/pubmed/30186877
http://dx.doi.org/10.1155/2018/7653904

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