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TERT and Akt Are Involved in the Par-4-Dependent Apoptosis of Islet β Cells in Type 2 Diabetes
Islet β cell apoptosis plays an important role in type 2 diabetes. We previously reported that Par-4-mediated islet β cell apoptosis is induced by high-glucose/fatty acid levels. In the present study, we show that Par-4, which is induced by high-glucose/fatty acid levels, interacts with and inhibits...
Autores principales: | Liu, Chen, QiNan, Wu, XiaoTian, Lei, MengLiu, Yang, XiaGuang, Gan, WeiLing, Leng, ZiWen, Liang, Ling, Zhang, GangYi, Yang, Bing, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112224/ https://www.ncbi.nlm.nih.gov/pubmed/30186877 http://dx.doi.org/10.1155/2018/7653904 |
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