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NRF2 Activation Inhibits Both TGF-β1- and IL-13-Mediated Periostin Expression in Fibroblasts: Benefit of Cinnamaldehyde for Antifibrotic Treatment

Systemic fibrosing or sclerotic disorders are life-threatening, but only very limited treatment modalities are available for them. In recent years, periostin (POSTN), a major extracellular matrix component, was established by several studies as a novel key player in the progression of systemic fibro...

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Detalles Bibliográficos
Autores principales: Mitamura, Yasutaka, Murai, Mika, Mitoma, Chikage, Furue, Masutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112270/
https://www.ncbi.nlm.nih.gov/pubmed/30186543
http://dx.doi.org/10.1155/2018/2475047