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Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca(2+)-dependent HIF-1α/ERRα circuit
Heme oxygenase-1 (HO-1) exerts beneficial effects, including angiogenesis and energy metabolism via the hypoxia-inducible factor-1α (HIF-1α) and peroxisome-proliferator-activating receptor-γ coactivator-1α (PGC-1α)/estrogen-related receptor α (ERRα) pathways, respectively, in astrocytes. However, ev...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112640/ https://www.ncbi.nlm.nih.gov/pubmed/30153269 http://dx.doi.org/10.1371/journal.pone.0202039 |