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Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion

Endogenous retroviruses (ERVs) are proviral sequences that result from colonization of the host germ line by exogenous retroviruses. The majority of ERVs represent defective retroviral copies. However, for most ERVs, endogenization occurred millions of years ago, obscuring the stages by which ERVs b...

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Detalles Bibliográficos
Autores principales: Löber, Ulrike, Hobbs, Matthew, Dayaram, Anisha, Tsangaras, Kyriakos, Jones, Kiersten, Alquezar-Planas, David E., Ishida, Yasuko, Meers, Joanne, Mayer, Jens, Quedenau, Claudia, Chen, Wei, Johnson, Rebecca N., Timms, Peter, Young, Paul R., Roca, Alfred L., Greenwood, Alex D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112702/
https://www.ncbi.nlm.nih.gov/pubmed/30082403
http://dx.doi.org/10.1073/pnas.1807598115