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Dynamic redox balance directs the oocyte-to-embryo transition via developmentally controlled reactive cysteine changes

The metabolic and redox state changes during the transition from an arrested oocyte to a totipotent embryo remain uncharacterized. Here, we applied state-of-the-art, integrated methodologies to dissect these changes in Drosophila. We demonstrate that early embryos have a more oxidized state than mat...

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Detalles Bibliográficos
Autores principales: Petrova, Boryana, Liu, Keke, Tian, Caiping, Kitaoka, Maiko, Freinkman, Elizaveta, Yang, Jing, Orr-Weaver, Terry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112717/
https://www.ncbi.nlm.nih.gov/pubmed/30082411
http://dx.doi.org/10.1073/pnas.1807918115