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LEE011 and ruxolitinib: a synergistic drug combination for natural killer/T-cell lymphoma (NKTCL)

Natural killer/T-cell lymphoma (NKTCL) is an aggressive non-Hodgkin lymphoma that has been facing limited success with conventional treatments, urging for the discovery of alternative strategies. Recent studies including ours have revealed that EZH2 and JAK-STAT signalling pathways are key contribut...

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Detalles Bibliográficos
Autores principales: Hee, Yan Ting, Yan, Junli, Nizetic, Dean, Chng, Wee-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112754/
https://www.ncbi.nlm.nih.gov/pubmed/30159126
http://dx.doi.org/10.18632/oncotarget.25835