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Tissue transglutaminase 2 expression is epigenetically regulated in human lung cancer cells and prevents reactive oxygen species-induced apoptosis

PURPOSE: Tissue transglutaminase 2 (TG2) is a stress-regulated protein and associated with cancer cell survival. However, the effects of TG2 expression in human non-small-cell lung cancer (NSCLC) cells on reactive oxygen species (ROS) production and redox homeostasis have not been fully elucidated....

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Detalles Bibliográficos
Autores principales: Lee, Ming-Yang, Wu, Ming-Fang, Cherng, Shur-Hueih, Chiu, Ling-Yen, Yang, Tsung-Ying, Sheu, Gwo-Tarng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112806/
https://www.ncbi.nlm.nih.gov/pubmed/30197536
http://dx.doi.org/10.2147/CMAR.S155582