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PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients

Characterization of CD8+ T cells in the tumor microenvironment (TME) is important to predict responses to checkpoint therapy. The TME in multiple myeloma is the bone marrow, which also is an immune organ where immune responses are generated and memory cells stored. The presence of T cells with other...

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Detalles Bibliográficos
Autores principales: Sponaas, Anne-Marit, Yang, Rui, Rustad, Even Holth, Standal, Therese, Thoresen, Aud Solvang, Dao Vo, Camilla, Waage, Anders, Slørdahl, Tobias S., Børset, Magne, Sundan, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112830/
https://www.ncbi.nlm.nih.gov/pubmed/30174794
http://dx.doi.org/10.18632/oncotarget.25882