Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway

Angiogenesis is a hallmark for cancer development because it is essential for cancer growth and provides the route for cancer cell migration (metastasis). Understanding the mechanism of angiogenesis and developing drugs that target the process has therefore been a major focus for research on cancer...

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Detalles Bibliográficos
Autores principales: Ai, Nana, Chong, Cheong-Meng, Chen, Weiting, Hu, Zhe, Su, Huanxing, Chen, Guokai, Lei Wong, Queenie Wing, Ge, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112840/
https://www.ncbi.nlm.nih.gov/pubmed/30174789
http://dx.doi.org/10.18632/oncotarget.24110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112840/
https://www.ncbi.nlm.nih.gov/pubmed/30174789
http://dx.doi.org/10.18632/oncotarget.24110

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