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Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway
Angiogenesis is a hallmark for cancer development because it is essential for cancer growth and provides the route for cancer cell migration (metastasis). Understanding the mechanism of angiogenesis and developing drugs that target the process has therefore been a major focus for research on cancer...
Autores principales: | Ai, Nana, Chong, Cheong-Meng, Chen, Weiting, Hu, Zhe, Su, Huanxing, Chen, Guokai, Lei Wong, Queenie Wing, Ge, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112840/ https://www.ncbi.nlm.nih.gov/pubmed/30174789 http://dx.doi.org/10.18632/oncotarget.24110 |
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