The Role of the L-Type Ca(2+) Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy

Heterozygous mice (αMHC(403/+)) expressing the human disease-causing mutation Arg403Gln exhibit cardinal features of hypertrophic cardiomyopathy (HCM) including hypertrophy, myocyte disarray, and increased myocardial fibrosis. Treatment of αMHC(403/+)mice with the L-type calcium channel (I(Ca-L)) an...

Descripción completa

Detalles Bibliográficos
Autores principales: Viola, Helena M., Johnstone, Victoria P.A., Cserne Szappanos, Henrietta, Richman, Tara R., Tsoutsman, Tatiana, Filipovska, Aleksandra, Semsarian, Christopher, Seidman, Jonathan G., Seidman, Christine E., Hool, Livia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
PRE-CLINICAL RESEARCH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113168/
https://www.ncbi.nlm.nih.gov/pubmed/30167506
http://dx.doi.org/10.1016/j.jacbts.2015.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113168/
https://www.ncbi.nlm.nih.gov/pubmed/30167506
http://dx.doi.org/10.1016/j.jacbts.2015.12.001

Ejemplares similares