RGMa mediates reactive astrogliosis and glial scar formation through TGFβ1/Smad2/3 signaling after stroke

In response to stroke, astrocytes become reactive astrogliosis and are a major component of a glial scar. This results in the formation of both a physical and chemical (production of chondroitin sulfate proteoglycans) barrier, which prevent neurite regeneration that, in turn, interferes with functio...

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Detalles Bibliográficos
Autores principales: Zhang, Rongrong, Wu, Yanping, Xie, Fei, Zhong, Yiliang, Wang, Yu, Xu, Mengxue, Feng, Jinzhou, Charish, Jason, Monnier, Philippe P., Qin, Xinyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113216/
https://www.ncbi.nlm.nih.gov/pubmed/29396549
http://dx.doi.org/10.1038/s41418-018-0058-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113216/
https://www.ncbi.nlm.nih.gov/pubmed/29396549
http://dx.doi.org/10.1038/s41418-018-0058-y

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