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Structural basis of cell wall peptidoglycan amidation by the GatD/MurT complex of Staphylococcus aureus

The peptidoglycan of Staphylococcus aureus is highly amidated. Amidation of α-D-isoglutamic acid in position 2 of the stem peptide plays a decisive role in the polymerization of cell wall building blocks. S. aureus mutants with a reduced degree of amidation are less viable and show increased suscept...

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Detalles Bibliográficos
Autores principales: Nöldeke, Erik R., Muckenfuss, Lena M., Niemann, Volker, Müller, Anna, Störk, Elena, Zocher, Georg, Schneider, Tanja, Stehle, Thilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113224/
https://www.ncbi.nlm.nih.gov/pubmed/30154570
http://dx.doi.org/10.1038/s41598-018-31098-x