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Metabotropic Acetylcholine and Glutamate Receptors Mediate PI(4,5)P(2) Depletion and Oscillations in Hippocampal CA1 Pyramidal Neurons in situ
The sensitivity of many ion channels to phosphatidylinositol-4,5-bisphosphate (PIP(2)) levels in the cell membrane suggests that PIP(2) fluctuations are important and general signals modulating neuronal excitability. Yet the PIP(2) dynamics of central neurons in their native environment remained lar...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113233/ https://www.ncbi.nlm.nih.gov/pubmed/30154490 http://dx.doi.org/10.1038/s41598-018-31322-8 |